Bills vs. 49ers drive-by-drive updates

ORCHARD PARK, NY (WHEC) – The Buffalo Bills host the San Francisco 49ers on Sunday Night Football in a week 13 clash.

The Bills (9-2) are coming off six-straight wins while the Niners (5-6) have lost back-to-back games coming in.

The Bills will be without rookie wide receiver Keon Coleman for the third-straight game but do get back All-Pro linebacker Matt Milano after suffering a bicep injury in the preseason.

San Francisco will be without starting left tackle Trent Williams and defensive end Nick Bosa. Starting quarterback Brock Purdy returns to the lineup after missing last week’s game with an injury.

The game airs on NBC, kickoff is scheduled for 8:20 pm. After the game, News10NBC will show highlights and break down the game on air.